Besides what is written in the example config, are there any specific settings I can change for 1080 Ti's? At best I'm getting 0.63 cpd per card (with an i5 6600K) but most get around 45-50 cpd (G4400) on Linux. They have the same settings.

I'm assuming that the G4400 isn't powerful enough to get up to 0.6 cpd? I'm using the default Nvidia-settings that are already present in the config as comments.