How does it crash, a window opens saying the app has crashed, or ?
It crashes with a blue screen!
That was a joke (a bad one)

Usually happens overnight. I'll wake up to find one of two things:
1) System has restarted on its own.
2) System is hung. I can't even get the monitor to wake up (using on board video, do not have remote capability yet). However, the cards are all behaving like they are hashing in the sense that they fans are running around~2000 RPM but the pool web page says no hashes from my rig. My only option at this point is to force restart the system.
It's pretty consistent that it will do this in ~24 hour timeframe.