Of course it is possible, you can compare btc into alt or even in fiat and other things but honestly this be shouldn't. For me, btc is the superior so it's pointless to compare it onto alts because alts is expected to get beaten in every aspect of the game unless btc already fall down from the number 1 spot and replaced by the other (now it will become comparable).

Instead of btc ~ alt comparison, I think it's much easier to accept the alt ~ alt comparison in terms of market price, volume of holders and potentials of booming. When it comes to platforms, we should not compare it because every coin focuses on a particular purpose or application and we should respect that.