Right now I'm pretty much in the same situation, but I started with Primecoin.  Looking towards Dual L5420's as those should in theory pull 3400-3600 Primes/Sec.  Currently with the 6500Primes/sec I use I pull about 0.08XPM/hour.  Figures are depressing, but totaled up with the L5420 lot I'm looking at I could see about 500$ profit, that's granted my rough calculations are correct.  That's the most profitable way I see it now, other than trading. Primecoin seems to piggyback heavily off of BTC, as I use BTC-e.  So it fluctuates with that, or so it seems.  Recently it shot up and made mining alot more profitable.  I plan on sticking with Primecoin for a while.  (CPU mining seems to be most profitable, in terms of mining.  At least in my eyes.)