First of all, you need to hold the cryptocurrency exclusively on the hardware wallet. I prefer firmware wallet Ledger. In the Ledger Blue version, up to 10 coins can be wounded at the same time.
The safenest depends on ways we will use it having trezor or ledger can definitely help. And in terms of exchanges and visiting sites just avoid to be phished and always find time to learn to study the every crypto. It's good to know more and be guided.