I would be very wary of using Cryptsy -- they recently had a serious bug which allowed users to withdraw BTC from their wallets that they didn't actually have. (Thereby subtracting them from other peoples' wallets, of course.)
Idk, all these "OMG a software ERROR!!!!" Seem a bit overblown. These things happen with major banks too--not always where they'll even cover you after. Cryptsy has good capabilities (though I would like to see the fees fall, especially withdrawal fees) and is seeking to become a compliant entity. I think it would be wise for them to do some re-architecting of the back-end after that issue and test it from all sorts of ends, but the moral of the story (for any exchange) is probably that, if you have the option, put eggs in multiple baskets.