Hey Alex,

There are a few ways to do this but the best way to deal with the update is to have a cheap computer (test system) like your main rigs minus GPU's or if you can afford it one gpu 4GB above.

I say this so you won't need to have a machine down while you figure out software & hardware issues.
*The easy (fast) fix is to limit the OS partition drive of your HDD or a 120GB ssd and max out the VR to50000-60000

My large system has a 120Gb ssd and it tells me every other day or so that an issue needs fix because not enough room to update (learn more) then exit the settings screen but I still see the miner working in the background of that message, so it does not pose an issue atm.

I always suggest if its running with restarts every once and awhile let it go and keep an eye on it through ethermine.org screen to check if your miner is up (15 minute delay in reporting)

The more you learn and take notes of your issues will make you a better problem solver and then sometimes computer hardware & software get a mind of their own-really do,lol

Need any help feel free to ask but must be precise on details.