If they sell enough to crash eth mining. It will crash gpu mining.
The E3 isn't really any more efficient than the GPU miners so I don't see how these units will make any impact at all. Like someone else pointed out there weren't enough of these sold to make a difference. Run the hash/energy consumption numbers and you will verify for yourself that this is no competitive advantage with the E3.
For those who bought the first batch E3 worth $800, the price point is a clear competitive advantage.
Also, if pay closer attention to the E3 notes, it says that the advertised hashrate and power consumption is only conservative and would probably change once it is delivered. We could be looking at 180-200 MH with less than 800 watts power consumption. Thats better efficiency than any GPU out there as of today.