I haven't had many issues with Cryptsy. Given the obscene daily growing volume on all crypto sites, I'm surprised it has as few problems it does.
I'd probably be saying otherwise if I transferred in a BTC and it didn't show up for six days like it did at Coins-e, who still haven't contacted me!
Vern, it might help to put a disclaimer on the site about heavy ticket volume.
BTW, Coins-e.com did eventually contact me and fix the issue!