Without much information, i only could suggest :
1. Re-install or update (Newest version is 3.1.3 BTW) your Electrum wallet, there's chance the application corrupted.
2. Check if another application working properly. If other application don't work properly, try to reinstall/repair your OS since important system files might be missing or corrupted.
Those two steps are defenatly a good start, i would like to add the following step... It's a bit harder than the steps ETFbitcoin proposed, so i'd keep this step as a last resort:
- use a different pc/laptop or at least a different user account to run the latest standalone version of electrum and restore your wallet from seed, make sure the green indicator in the right bottom of the screen is green, make sure your system is clean, make sure the root disk isn't full... Enable coin controll and double check there are unspent outputs you can spend. If everything is OK, and you still can't spend your BTC, i'm running out of idears

Good luck