Bitcoin as the main currency and doge as the alternative currency. Doge is the best coin for gambling because the fee is low and the confirmation speed is fast.
Just be careful it should not happen that you gamble with btc and lose that portion and after sometime you realize that btc has started to reach sky and the gamble loss becomes a huge amount if considered in the rising prices of btc in coming time.
Why you need to be careful only with the bitcoins there are various website which accepts the bitcoin or alts you should be careful with every gambling websites mate, If you want to ignore the loosing completely you should go away from betting or any games with the gambling mate.
Then you need to check the best place to gamble if you want to make the money out it. When you go for sports betting you may able to do some profit than other website for sure mate.