As long as no one will discover your private equity keys and you are also using ledger wallet your bitcoin will be safe but investor is not safe of losing the value of his or her money from bitcoin when it dip. But it can also be recover if you keep on holding and profit may come too.
There is nothing safe in full, at 100%. Your bank account can be hacked, a wallet with cash to steal, a house to rob. The degree of risk is almost the same everywhere. Protect your computer. Keep your personal keys and keys secure. Do whatever is possible for your own safety