Yes, OTC trades is one use. Weave is unique in the way it allows separate blockchains to interact in a trustless environment without leaving a record of it. 'Alice' and 'Bob' can exchange Bitcoin and Ethereum, for example, without either asset leaving their control until the exchange. All transactions on the Weave chain are encrypted, cannot be tracked, and are secured by the Weave chain. It could be compared to Changelly, but the Weave system is decentralized and double blind. The only fees incurred are on the asset's blockchain when it is locked into a node, fully controlled by the user, yet can be unlocked for no fee. This could be accomplished for no fee if you have someone else send Bitcoin for example, to a locked node Bitcoin address.