I just upgrade to the Adrenalin 18.6.1 driver on Win 10 on my 6 gpu rig.
I ran DDU, installed the new 18.6.1 driver, set to compute mode, run pixel patcher, restarted the pc.

When I launch the Claymore miner v11.8, the miner doesn't get past the following

ETH: 6 pools are specified
Main Ethereum pool is eth-us-east1.nanopool.org:9999

Then I see the following:
Miner cannot initialize for 5 minutes, need to restart miner!

All cards are are detected in device manager
In the registry, EnableUlps=0

Any ideas on how to resolve this ?