TBH I would advise stick to top 20 coins, Cardano is my opinion will be a sure thing come the bull run, likewise will be Neo, these are huge space to grow in this area so I would choose these
in any case, I choose the first coin and this is the epherium. I am confident in the near future of the etherium and the real demand for ETH in society for quite a long time. But I have still views on ripple, because to date this coin well connects the crypto currency with the banking system.