For some reason, I have my faith on Bittrex.
But everyone is talking about coins and ICOs but I tend to believe most of the exchanges will be closed soon.
An exchange is a hell of a thing.
I think that in the end all of them will be obsolete and unneeded. Why pay fees to exchanges when you can trade directly etc. It'll be done in the future somehow.
I would not say they will be obsolete though, but over time, decentralized exchanges will pop up and start taking the space bit by bit until they get better.
Nevertheless, when it comes to volume though, we really do not have any choice for now, and all we can do is to simply make use of the ones available with at least a bit of trust. I would say for now, bittrex and binance are still a lot more better when it comes to security, volume and some other features, but for binance, top notch on fees and volume.