I think Kakushin is way better than Loci. Loci’s Blockchain-Focused Intellectual Property Platform for Inventors and Entrepreneurs to Be Added to UpChannel’s dApp Marketplace, but Kakushin allows innovators to search and register for any patent on Kakushin’s IPR, Kakushin has greatly reduced the difficulty that innovators face in establishing basic copyright protection for their innovations and for reducing the ill-effects of copyright violations. Kakushin’s approach is essentially centered around efficient market validation and risk mitigation so, I guess Kakushin will always be my first choice over Loci or all the other IP based ICOs.