It depends on the motive for acquiring the 250eth.If you wish to use as store of value or as an investment, then you may need to specify a time frame for your holding,after which you find a suitable exit by selling off. However if you acquired the Ether for trading to take profit,selling point will be referenced against your initial buying price. Better still if the need for fiat arise you may sell off some. Either way its a win-win eth will do well later, most Blockchain startups use the eth Blockchain