yes it is different because bitcoin is a digital currency that uses peer to peer networks and uses a database for its distribution. while ethereum is a chain platform block and functions like a virtual machine.
The difference between etherium and bitcoin is the fact that bitcoin is nothing more than a currency, whereas etherium is ledger technology that companies are using to build new programs, Both bitcoin and etherium operate on what is called blockchain technology however etherium is far more robust. If bitcoin was version 1.0, etherium is 2.0, allowing for the building of decentralized applications to be built on top of it.