I've got 2 instances of the proxy for two pools - so it's 4 instances of the proxy running. The Blades and the Cube go to their own pair of proxies.
So, I have 4 shortcuts in Windows startup - Cube Eligius, Cube BTCGuild, Blades Eligius and Blades BTCGuild. This allows the miners to swap between pools automatically if one pool is down. All 4 shortcuts point to the same .exe so no real issues.
2 blades sharing a proxy? Eligius is vardiff last i checked, so you may want to consider having yet another proxy instance or two so the blades aren't sharing... I will reiterate yet again that slush's proxy does not handle well multiple workers with different share difficulties, resulting in unsubmitted shares and lost profits.
Luke-JR, please please please add long poll to the bfgminer proxy so we don't have to deal with this... Or if slush would fix the stratum proxy, that would be great too. Or ASICminer could implement stratum natively in the firmware - I'd be okay with that too.