Biblical prophets are the one that have really see the future and most of the prophecies has come to pass as stated. The end is very near then when we begin and that is why we should be close to God like never before. We are living in the earth and it seems all the humanity are against God.
Actually, the will of mankind is against God. As sinners, we can't understand the way that God thinks in His perfect desiring for us to be holy like He is. We might come close at times. But we never quite understand.
This is why we die. We die so that we can let go of all imperfection. Then, god will take the essence of our spirits/souls, and place them into perfection in the new life in Heaven.
So, yes! All of humanity is against God, even though He has found some of us who are so weak spiritually, that He can work saving faith in us.

If you do believe in the Bible, wouldn't you believe that God is a loving creator? According the Bible, He created the whole Earth for us. You could compare Him to a parent. Even Jesus referred to Him as Father. If you imagine a parent-child relationship on Earth, you can see some similarities. Parents on Earth try to create good environments for their children. They try to give them lots of opportunities. Their children don't always obey and they don't always appreciate everything they've been given. I don't think you you can say though that the children are against their parents. They just don't understand everything completely yet.