It all depends on your personal investment goals. If you have a longer outlook it may make more sense to hold and wait for a 10x-50x altcoin rise, however if you have less time or are not as risky you may want to set your limit sell orders at 1.5-2x cost. It is also smart to set stop loss orders if you cannot afford to lose more than a certain amount. These investments are volatile and move around quite a bit on a daily basis. Good luck!