My suggestion is Bitcoin and Ethereum.. Cause, a lot of people still hold and trade with these pair..
You don't need to doubt on this two great coin before fore sure it can give you a big profit in the future. If you are just newbie in this market then investing with ETH and BTC is really advisable. Don't just invest on any coins without any understanding about it. Try to study more the market, so you will be know where to invest next time so for now, better to go for BTC and ETH.