Of course you should used most advantage exchange for trading. You can choose whice is easy to use for you. I don't like to recommend, I use bittrex. If you have enough time for trading than it's better to put your money on multiple exchange. Because hacking is dangerous virus on crypto market. You can follow more than one day chart it's totally depend on trends. If you can't make profits during buy time it's very difficult to profit on sale. There is no 100% safer way for trading. Trading is money circulation, so some one will lose and some will gain. If people find any safer way to trade than they will become millioner within short time. Btw, I like btc pair for trading.