I think it got differences, for the big gamblers, when they want to gamble using alt coin they also need to predict whether the alt coin price could go down or not, maybe today 1 trx is 3$ but if tomorrow change into 1$, then their capital is falling down, so gambling in alt coin does give extra risk to the gambler, but the casino need to adopted some alt coin, so the gamblers got more options and some alt coin got a better speed transaction and lower transaction fee, for gambling I like to used btc and doge, doge transaction fee is very cheap and it's easier to bet using doge, I don't need to count the fraction