There is no doubt that in the current situation it is better to trade only with those cryptocurrencies which have USD as basis currency and fix profit in USD. Also I try to increase only my USD. That's why I hold my all money in fiat.
I prefer to increase investment in US dollars, but also invest in bitcoin. For trading, I prefer bitcoin, because of historical factors, bitcoin is a crypto pioneer, which is certainly favored by the market. Don't put your eggs in one basket, that's the business principle. So there is no need to fear losing, because businesses only know two words: profit or loss.