If you are looking to trade cryptos with leverage Bitmex has always been the goto solution because they offer up to 100X leverage on perpetual contracts on Bitcoin.
Some issued with Bitmex are that they only take deposits in Bitcoin, are super complicated to use and their contracts on the alt coins expire like traditional futures.
I have seen a lot of news about a company that is about to Launch called Monfex. It looks like they will be offering leveraged perpetual contracts on over 10 coins and allow funding in USD and Euro in addition to Bitcoin.
Their advertising puts a lot of emphasis on simplicity. If they are easy to use, they are certainly worth a shot. Also there may be some potential arb opportunities with the financing rates between Bitmex and Monfex.