2 rigs with 12 gpus well optimezed (RX 580 and RX 570) doing 31,3 average mh/s, is doing around 376 mh/s. those rigs are using around 1800w from the wall.
Its mean your miners are not even close to optimized , your power draw at the wall should be under 1600 watts

with a "optimized" 12x RX580 rig

to answer your question, we have to stablish a base line. What's the meaning of PROFIT, for you? is winning 40$ a month what you would call profit???
Because that's the most you will get right now with an E3 paying 7 cents (suppose taxes included).
Current profitability with Bitmain E3 and 0.07$/kWh is actually around 60$/months 
40$ a months or 60$ a months / miner, yes i would call that as a profit for sure
If my miners are paid back already , then i would call that 40-60$/months/miners as a big profit

5 of my cards are doing 32,4 mh/s at 1240/2250 868mv. Are you sure what you are saying? i don't think so.
It's widely proved, that the best ratio performance - power consumption is 1240/2250 at something around 850 to 878mv depending on how good your card is.
i don't think it's wise for you to talk about "optimization" without actually pulling out numbers to discuss.