So far we have seen at least hundreds of "cryptocosmic" startups and nothing ground breaking has been accomplished yet. On the other hand, although Microsoft have been exploring Blockchain for quite some time, we saw this year, the rest of the top tech companies, Facebook, Amazon, Google, and Apple taking Blockchain seriously. It has to be seen when or how these dominant tech companies are going to use Blockchain to create new opportunities.
As far as cryptocosmic companies, if I take Blockchain/decentralization/Dapps/DAO (more innovations to come) as the basis then in the next ten years, maybe we would see some new decentralized ecommerce startups/existing ones like OpenBazaar capturing some real market share, but I think with all the data breaches/security concerns, social media would be one of the major sectors where crypto startups would compete.