Scrypt is going to hate ASIC Scrypt miners, it kinda defeats the purpose of being Scrypt. I hope the algos change so to keep the GPU mining market open to people and not be pooped on by the people with the most money.
Check out vertcoin, an Adaptive N-factor Scrypt coin, which ASICs will not be able to mine
https://bitcointalk.org/index.php?topic=404364.0I expect this to be the next LTC. But ASICs will be able to mine it in the future once it is profitable to design an FPGA/ASIC for it.
From the hundreds of coins out there now, how can anyone predict what will be the "next big thing"? Its a coin jungle out there, and the jungle is growing daily.