Hello JCE!
I got issue with FX 8350. Got 2 fx8350 in different MB. One doing fine with this config

"cpu_threads_conf" :
[
     { "cpu_architecture" : "auto", "affine_to_cpu" : 1, "use_cache" : true },
     { "cpu_architecture" : "auto", "affine_to_cpu" : 2, "use_cache" : true },
     { "cpu_architecture" : "auto", "affine_to_cpu" : 3, "use_cache" : true },
     { "cpu_architecture" : "auto", "affine_to_cpu" : 4, "use_cache" : true },
     { "cpu_architecture" : "auto", "affine_to_cpu" : 5, "use_cache" : true },
     { "cpu_architecture" : "auto", "affine_to_cpu" : 6, "use_cache" : true },
     { "cpu_architecture" : "auto", "affine_to_cpu" : 7, "use_cache" : true },
]

 But second one gives me error "Failed to allocate 2MB Large Page Scratchpad Buffer, using normal memory (slower)."
Same configs. Same UPlexa coin. Only difference is failed system have 4G ram and OK system got 16G ram. Is it a case or something else? Large pages are unlocked for both systems. Hashrate at monero v8 a same(~350H/s).

 Here is a log.

              +--------------------------------------+
              | JC Expert Cryptonote CPU Miner 0.33n |
              +--------------------------------------+


For Windows 64-bits
Analyzing Processors topology...
AMD FX(tm)-8350 Eight-Core Processor
Assembly codename: bulldozer
  SSE2    : Yes
  SSE3    : Yes
  SSE4    : Yes
  AES     : Yes
  AVX     : Yes
  AVX2    : No

Found CPU 0, with:
  L1 Cache:    16 KB
  L2 Cache:  2048 KB, shared with CPU 1
  L3 Cache:  8192 KB, shared with CPU 1, 2, 3, 4, 5, 6, 7
Found CPU 1, with:
  L1 Cache:    16 KB
  L2 Cache:  2048 KB, shared with CPU 0
  L3 Cache:  8192 KB, shared with CPU 0, 2, 3, 4, 5, 6, 7
Found CPU 2, with:
  L1 Cache:    16 KB
  L2 Cache:  2048 KB, shared with CPU 3
  L3 Cache:  8192 KB, shared with CPU 0, 1, 3, 4, 5, 6, 7
Found CPU 3, with:
  L1 Cache:    16 KB
  L2 Cache:  2048 KB, shared with CPU 2
  L3 Cache:  8192 KB, shared with CPU 0, 1, 2, 4, 5, 6, 7
Found CPU 4, with:
  L1 Cache:    16 KB
  L2 Cache:  2048 KB, shared with CPU 5
  L3 Cache:  8192 KB, shared with CPU 0, 1, 2, 3, 5, 6, 7
Found CPU 5, with:
  L1 Cache:    16 KB
  L2 Cache:  2048 KB, shared with CPU 4
  L3 Cache:  8192 KB, shared with CPU 0, 1, 2, 3, 4, 6, 7
Found CPU 6, with:
  L1 Cache:    16 KB
  L2 Cache:  2048 KB, shared with CPU 7
  L3 Cache:  8192 KB, shared with CPU 0, 1, 2, 3, 4, 5, 7
Found CPU 7, with:
  L1 Cache:    16 KB
  L2 Cache:  2048 KB, shared with CPU 6
  L3 Cache:  8192 KB, shared with CPU 0, 1, 2, 3, 4, 5, 6

Preparing 7 Mining Threads...

+-- Thread 0 config ------------------------+
| Run on CPU:            1                  |
| Use cache:             yes                |
| Multi-hash:            no                 |
| Assembly module:       bulldozer          |
+-------------------------------------------+

+-- Thread 1 config ------------------------+
| Run on CPU:            2                  |
| Use cache:             yes                |
| Multi-hash:            no                 |
| Assembly module:       bulldozer          |
+-------------------------------------------+

+-- Thread 2 config ------------------------+
| Run on CPU:            3                  |
| Use cache:             yes                |
| Multi-hash:            no                 |
| Assembly module:       bulldozer          |
+-------------------------------------------+

+-- Thread 3 config ------------------------+
| Run on CPU:            4                  |
| Use cache:             yes                |
| Multi-hash:            no                 |
| Assembly module:       bulldozer          |
+-------------------------------------------+

+-- Thread 4 config ------------------------+
| Run on CPU:            5                  |
| Use cache:             yes                |
| Multi-hash:            no                 |
| Assembly module:       bulldozer          |
+-------------------------------------------+

+-- Thread 5 config ------------------------+
| Run on CPU:            6                  |
| Use cache:             yes                |
| Multi-hash:            no                 |
| Assembly module:       bulldozer          |
+-------------------------------------------+

+-- Thread 6 config ------------------------+
| Run on CPU:            7                  |
| Use cache:             yes                |
| Multi-hash:            no                 |
| Assembly module:       bulldozer          |
+-------------------------------------------+

Cryptonight Variation: Cryptolight-uPlexa fork of Dec-2018

Low intensity.

Starting CPU Thread 0, affinity: CPU 1
Thread 0 successfully bound to CPU 1
Allocated shared Large Page at: 00000225f2a00000
Allocated 2MB Cached Large Page Scratchpad Buffer for CPU 1 of NUMA node 0 at: 00000225f2c00000

Starting CPU Thread 1, affinity: CPU 2
Thread 1 successfully bound to CPU 2
Reuse part of 2MB Cached Large Page Scratchpad Buffer at: 00000225f2d00000

Starting CPU Thread 2, affinity: CPU 3
Thread 2 successfully bound to CPU 3
Failed to allocate 2MB Large Page Scratchpad Buffer, using normal memory (slower).

Starting CPU Thread 3, affinity: CPU 4
Thread 3 successfully bound to CPU 4
Failed to allocate 2MB Large Page Scratchpad Buffer, using normal memory (slower).

Starting CPU Thread 4, affinity: CPU 5
Thread 4 successfully bound to CPU 5
Failed to allocate 2MB Large Page Scratchpad Buffer, using normal memory (slower).

Starting CPU Thread 5, affinity: CPU 6
Thread 5 successfully bound to CPU 6
Failed to allocate 2MB Large Page Scratchpad Buffer, using normal memory (slower).

Starting CPU Thread 6, affinity: CPU 7
Thread 6 successfully bound to CPU 7
Failed to allocate 2MB Large Page Scratchpad Buffer, using normal memory (slower).
Devfee for CPU is 1.5%

04:07:27 | Uplexa (UPX) Mining session starts!