I find it an interesting topic, but I'd like to see some good peer-reviewed studies on the effectiveness of some of these things, as well as the long term side effects.
It seems to me that many people just pop a variety of pills of varying dosages and experiment on themselves in a haphazard way.
While you'd think personal experience - ie 'what works for me' would be a good guide - I'm not so sure.  I know from my own experiments with diet that it's very hard to draw valid conclusions as there are so many variables.

The only things I take that are remotely nootropical are caffeine (tea,coffee,chocolate) and nicotine.  I don't smoke - I just occasionally take a nicotine tablet (supposedly to help quitters -lol) as a mild mental pep up and general stress reliever.