I'm partial to text-to-speech since I've been watching a lot of vids that incorporate it into their comedy.
I've seen some really funny cartoon-type, self-written parodies on youtube using the text-to-speech and I wouldn't be disappointed if someone made a very good one. That actually might be a better idea than a live action one IMO. There's got to be software that allows you to make one, because I've seen a few made by different people--not sure what the name is. I had one video that I liked, but now I can't find it. It had to do with ER nurses vs. critical care nurses and it was funny as all hell.
Someone please wake me up when it's time to cough up the merits for a video. As I said, I'll be happy to be generous as long as it's funny and well-made.