You can open pairs with BTC, ETH and USD. These are safest pairs and the favorites of all traders. You can also consider opening pairs with TRX and XLM. Many traders patronize these two also, and traders love those pairs in which both are feasibly and highly tradable. For instance, they trade their coins with ETH and then they will also play ETH in the market. That way, they can make double profit. Anyway, there's no loss in trying. Who knows, pairs with these coins might click.