A project that I know of (ShareRing) already started building their blockchain using Cosmos/Tendermint, but it's still very early. They said it is still in beta last time I checked and they've been doing commit/upgrade by themselves. So probably, Cosmos is not production ready but you can start using it and fix the bugs by yourself.
But according to Cosmos blog update, they'll roll out mainnet soon, so I assume it has become better. Why don't you try and make a testnet first?
We would make sure it works before deploying the main network, but we want to come to a definitive decision on what framework to use very soon.