I think it's possible, look at the memory requirement for cryptonight or ethereum, it may have a performance hit due to the extra pieces.
ASIC's are possible, but not anywhere near cost effective (half a million R&D?)
Ok, I have one reason I believe its
not possible, let me e-mail you that reason and then please post if you believe it is not advantageous/feasible to port biblepay to GPU.
Ok based on that I would concede gpu performance would be stifled a great deal.. I'll admit you thought quite a bit when putting this together.