could you share me your command string? my 780 autotuning keeps crashing... on scrypt
cudaminer.exe -l 14x8 -o stratum+tcp://fry.minebig.com:3341 -u slickleg64.1 -p p
Just updated to latest cudaminer today, Make sure you have latest nvidia drivers and restart or it does crash.
a 780 should also get quite a high hashrate, look online for a good config