Also one of the major ASS propositions of bitcoin remains on the individual level to empower individuals in the retention and the movement of their value, and perhaps only a few BIGGER type institutions are recognizing some kind of concrete value in that kind of power and monetary sovereignty.. which is a BIGASS use case that is already here.. and not speculation
Individuals are not the same as big institutions
The latter have to play by the rules set of their respective governments lest they should suffer unfavorable consequences. So it is not so much about institutions, big or otherwise, as about acceptance of crypto by governments. But if there is such acceptance and embrace, will we ever want these big fish sticking around? In fact, I don't think they actually need crypto as they are cool with fiat being backed up by the government. This is not the case with simple people, though, as they are to pay the price for the government shenanigans with fiat money