We are not seeing that happening now but it is going to happen in future.  A time will come that any business that has not adopting bitcoin or blockchain technology will not survive including big online store like amazon and Ali express.  However bitcoin need to be a bit stable for it to used as a mode or medium of exchanging goods and services.  The up and down of the market is the many reason why big wholesales and retails business cannot used it.  Amazon will certainly adopt bitcoin in future but the time is not what we can tell now.