cgminer.exe --scrypt -o stratum+tcp://pool.com -u worker -p pass -I 18 -w 256 -g 1 --thread-concurrency 24000 --gpu-fan 85 --lookup-gap 2 --gpu-engine 1120 --gpu-memclock 1500 --gpu-powertune 20
330 kh/s on this conf
I think that it is not a problem of cgminer configuration, because I tried a lot of this and always hash rate is similar.
Problem is propably somewhere else, but the question is where?

The problem is actually known: VRAM latency. There's a thread for 280x:
https://litecointalk.org/index.php?topic=12369.0Unfortunately 270's don't seem to be prioritary...
Instead, if this is becoming frustrating, I suggest you mine a non-scrypt coin like:
http://max.1gh.com/