If we purely speak about how to get the maximum profit out of a coin we want to speculate in or we want to trade, thinking and deciding about the exchange is the first step and for that, you need to understand why you should pick a particular exchange. What I do is that I go through the reviews of the users of the exchange and check the trading volume over their website. This is important to know the number of people who use an exchange because it reflects the potential and prestige of the exchange.