Quark was added to
https://c-cex.com today, so I started testing it out. It is like BTC-E.com with USD access and trollbox - but it's all just faster and nicer. Given that Quark confirmations take only 3o seconds, trading on this new C-Cex.com is simply AWESOME and FUN!!! Deposits take less than 1 minute and withdrawals arrive at your wallet INSTANTLY!!! (although, because it is Quark still take 30 seconds to confirm).
It is a new site, but if there is enough trading volume there, we can forget about Cryptsy.com and BTC-E.com altogether.