It all depends on your risk tolerance. I like to gamble on lower tier coins every now and then but I only use a small amount of money. looking back at the historical charts you an see how fast some of these coins can move. They can go 100x in a few days which is pretty crazy.
Lower tier coins in this market are a great opportunity for you to make a profit but the risk will be huge if you don't have a clear appreciation of that coin. I think this market always has a lot of surprises and it can easily make us get rich very quickly in just one day but can also take away all your assets in just a few hours so if If you choose the right time to invest then good for you. Everyone wants to earn a profit of 1000% in this market but to do that, you need to have the right consideration and make many suitable choices for your portfolio.