While no one has ever gone broke taking profits, it does reduce your capital investment. Unless you want to watch charts and try timing to sell at highs and re buy at lows you are reducing the amount of btc you have in the game. If you purchased and held you can relax and not watch daily prices. That is if you believe in btc for the long term.
For now BTC has begun to show more price increases and if anyone has the chance to buy at a price of one hundred million he has already gained a lot of profit if the trader buys in more than one amount, look at the BTC market that has started to green again until today.