bzedge, BCRM, rito and mix are examples of low diff coins. Most profitable right now? no, but you are doing speculative mining, right?
So profit may come long after.
If you are not against top-100 tokens, try to mine Grin. This cryptocurrency is based on the Mimblewimble protocol. This network is distinguished by increased confidentiality, scalability and reduced blockchain size. Despite the limited supply of coins, Grin has already gained recognition even among altcoin opponents. This is one of the best cryptocurrencies for mining in 2019.