Energy cannot be created or destroyed from within our Universe. This indicates a lack of equilibrium and hints that an inverse of energy must exist for existence to be possible.
And it does! Even before the hadron Collider experiments, we figured out that there are equal parts matter and antimatter in our universe. You put everything together, and it will all cancel each other out. Hadron Collider experiments substantiated that by showing that mini big bangs happen on a quantum level, which also have both matter and antimatter.