Daniel Negreanu was known for being good at poker, Winner of six World Poker Series (WSOP) bracelets and two World Poker Tour (WPT) titles. The poker ranking service Global Poker Index recognized Daniel Negreanu as the best poker player of the year 2014. What if he plays poker in a btc-based gambling site, will he manage to defeat an algorithm and bring a lot of profit?
It he is going to play at other players then there's a chance that can beat them. But if you are saying a algorithm or casino's colluding against him? Then definitely he doesn't have a shot at winning in my opinion.
But I agree that he is one of the best, reading the cards of his opponents is just eerie and even his contemporaries are amazed as how Daniel 'see' their card.