It seems crazy to me that people invest so much capital into margin trading. IMO, the benefit of doing it is that you don't need to invest and risk as much in the first place. I think the key is to be 100% comfortable with the fact that you could lose it all and decide whether the potential gains in the outcome of a successful trade is worth the risk of losing it all if unsuccessful. It is essentially a gamble if you use as much as 100x because a price action of just 1% can liquidate your position near instantly. I say either don't invest what you can't afford to lose, or don't use high leverage. If you wanna risk $100 for the opportunity to turn it into significantly more, then, by all means, go ahead - that seems like a fair trade-off to me. Just be aware of the risks. Also, you could try to hedge with an opposing position if possible.
I never get it myself. If you have $100 to trade, then trade with $100. Why would you ever want to pretend that you're trading with $1000? People forget:
To make profit as much as if you had $1000, you also have to risk that when you make a loss, you make a loss as if you had $10.
It's the same as borrowing money. Why would anyone ever borrow money to trade just makes me wonder. Trading is high risk as it is and the stats keep reminding us. But people just refuse to learn!