If you store coins in online wallets and if the site disappears in a sudden one day, you will lose everything.
Are you scared?
Everyone are scared of course specially if involves huge amount of cryptos but to minimize the risks never put your assets in exchanges wallet or only used the most trusted site like myetherwallet.com for ERC20 coins as this site will ensure to avoid mistakes because their reputation is at stake. You may use Nano Ledger S as an offline wallet that although expensive but its worth it specially huge assets are concern.