The real Karpeles has not been shown in ANY interview he has given or video clip. He always wears the same gesture of contented smug satis-fat-shion. What does that tell us?
Imho he is a sock puppet for somebody else that truly controls the strings...

The other possibility is that he is an almost perfect sociopath, unable to have an emotional grasp of what's happening around him.
In both instances, Karpeles remaining as CEO of Mt.Gox. is a guarantee at this stage that there is no beneficial outcome for the enterprise. He has isolated himself in order to protect himself instead of reaching out and searching allies.  Anybody else in that position would have recruited an able spokesperson to confront the situation. "Oh the hugemanatee!"